ea0026p500 | Bone/calcium/Vitamin D | ECE2011
Piedra M
, Garcia-Unzueta M T
, Berja A
, Riancho J A
, Valero C
, Paule B
, Lavin B A
, Amado J A
Background: Primary hyperparathyroidism (PHPT) affects mainly cortical bone. It is thought that PTH indirectly regulates the activity of osteoclasts by means of the osteoprotegerin/ligand of the receptor activator of nuclear factor-κβ (OPG/RANKL) system. Several studies have confirmed that OPG and RANKL loci are determinants of bone mineral density (BMD) in the general population. The aim of this study is to analyze the relationship between fractures and BMD and the ...